Separated at Birth: "Okay, Norman, you murdered my girlfriend, but you'll never kill agai...okay, one more, but then..."

L: Amazing Spider-Man #123 (July 1973), art by John Romita, Sr.
R: Friendly Neighborhood Spider-Man #10 (September 2006), art by Mike Wieringo, Karl Kesel, and Paul Mounts
(Click picture to Osborn-rap-sheet-size)